Association between the interleukin-1 family gene cluster and psoriatic arthritis
نویسندگان
چکیده
منابع مشابه
The Association between the Components and Features of Metabolic Syndrome in Patients with Psoriasis and Psoriatic Arthritis
Objective: Psoriasis (Pso) is associated with an increased risk of cardiovascular involvement. Metabolic syndrome (MetS) includes a group of classic cardiovascular risk factors with pro-inflammatory condition. The aim of the present study was to evaluate and compare the frequency of MetS in Pso patients with and without arthritis. Materials and Methods: This cross-sectional study was conducted...
متن کاملLack of association between interleukin-1 gene cluster polymorphisms and glaucoma in Chinese subjects.
PURPOSE A recent study identified single nucleotide polymorphisms (SNPs) within the IL-1 gene cluster at chromosomal locus 2q13 that were associated with reduced risk for primary open-angle glaucoma (POAG) in whites. The purpose of this study was to investigate the association between IL-1 SNPs and glaucoma in Chinese patients with either POAG or primary-angle closure glaucoma (PACG). METHODS...
متن کاملInterleukin-12 and interleukin-23 inhibition in psoriatic arthritis.
The cytokines interleukin (IL)-12 and interleukin (IL)-23 have been implicated variously in the pathogenesis of psoriasis and psoriatic arthritis (PsA). By corollary, the IL-12/23 inhibitor, Ustekinumab has been developed as an approved therapeutic for the skin and musculoskeletal syndrome of psoriasis / PsA. This review describes briefly the role of IL-12 and IL-23 in the pathophysiology of ps...
متن کاملThe link between obesity and psoriatic arthritis.
Psoriatic arthritis (PsA) is classified as a spondyloarthropathy and is characterised by synovitis, enthesitis, dactylitis and spondylitis, usually following the development of cutaneous and nail psoriasis. PsA patients have a higher prevalence of some comorbidities (obesity, metabolic syndrome, depression and premature cardiovascular disease) than patients with psoriasis (Pso) without arthriti...
متن کاملInterleukin-17 inhibition in psoriatic arthritis.
Greater understanding of the underlying disease process has led to the development of targeted therapeutic agents and innovative strategies in the treatment of psoriatic arthritis (PsA). This report addresses novel medications targeting the T helper 17 cell pathway, specifically those inhibiting interleukin-17A and its receptor, and discusses their role as effective therapies in the management ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 2006
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.21928